February 28 2007 While construction on the new

first_imgFebruary 28, 2007 While construction on the new Visitors Center entrance proceeds, access for physically challenged visitors has been temporarily moved to the parking area on the west-side of the North Vault. [Photo & text: sa] The maintenance department constructed a ramp to ease access. [Photo & text: sa]last_img

Rodolphe Belmer Eutelsat CEO Michel de Rosen will

first_imgRodolphe BelmerEutelsat CEO Michel de Rosen will step down in March 2016 and be succeeded by former Canal+ chief executive Rodolphe Belmer, the satellite operator has confirmed.De Rosen, who turns 65 next year, will remain non-executive chairman of the board of directors of Eutelsat until the end of his current mandate in November 2016.Belmer, who was dismissed as chief executive of Canal+ in July as part of a management board shakeup, will join Eutelsat on December 1 as deputy CEO, alongside existing deputy CEO and chief commercial and development officer Michel Azibert.Following a hand-over process he will take up the Eutelsat top-job on March 1, 2016. He will then be proposed as a member of Eutelsat’s Board at the annual shareholders’ meeting in November 2016.“It has been my great privilege since 2009 to serve as Eutelsat’s CEO and latterly as chairman and CEO. During this period, we have consistently put innovation at the heart of our service to customers, significantly expanding our geographic reach, and cementing our reputation as leaders in technical excellence,” said de Rosen.“I feel this is the right time to hand over the reins and am delighted to welcome Rodolphe Belmer in whom I have full confidence to build on these achievements and to take the company forward.”Lord Birt, vice-chairman of the board of Eutelsat Communications, praised de Rosen’s six-year leadership of the company and said he had “transformed Eutelsat into a truly global player”.“The Board of Directors is very pleased that Rodolphe Belmer will lead Eutelsat. With his extensive experience in broadcasting, his understanding of the trends shaping digital markets and his leadership, we are confident he has the skills to take Eutelsat forward in the evolving satellite communications landscape,” Birt added.Belmer left Canal+ over the summer and in August was reportedly hired by the new director-general of public broadcaster France Televisions, Delphine Ernotte, to lead a 12-strong strategic orientation committee.last_img read more

If you have not read the first three parts of this

first_imgIf you have not read the first three parts of this series, please do that first: They are a necessary prelude: Westphalian Orders’ End Part 1 Westphalian Orders’ End Part 2 Westphalian Orders’ End Part 3 I have thus far made quite a few arguments why the Westphalian order of states is in trouble. Presuming that I am correct, and that the current state model fails, the great question is what comes next? The Two Classes Impolitic though it may be, any sensible analysis of states in transition has to divide the inhabitants into two groups: the Rulers and the Ruled. We can seek tamer terms if we like (such as officials and citizens), but those terms invariably muddle the issue. There are two groups that matter: those that make orders and those who take orders. These two face massively different challenges and incentives; separating them clearly is the only way to arrange a reasonable discourse. I will begin with the rulers: Imagine being a big boss of a big country: You and your predecessors have promised free everything to your voters, but you have now failed to deliver. They are angry, but there’s nothing you can do; there are no more buyers for your bonds and inflation has made your currency almost worthless. You are out of options. At the same time, you can’t just walk away – being the boss is something you need. So, what do you do? Your first job will be to keep the people with you, rather than against you. You must give them someone else to blame and to make them feel horrible about the prospect of your system vanishing. Finding outsiders to blame is always easy. (Jews and immigrants being the perennial favorites.) Making people feel like they need you, however, isn’t so easy, especially when your promises have just come up painfully short. You need some majestic promise for them to believe in: something that makes them special, provides a credible promise of more than they deserve, and/or makes them part of some magical uber-entity. In other words, you need an appealing new myth. The problem, of course, is that large new myths are not created in a day, and certainly not by people who can’t deliver much. So, you have to use whatever respected myths remain, make them more grandiose, and run with them. (This is precisely what happened at the end of the Roman Empire, as I will explain in Free-Man’s Perspective.)Fall of the Roman Empire Right now, the only big myths are of the globalist strain, such as climate change, save the rainforest (or whales, or trees, or children, or…), the value of politically correct speech and so on. Judeo-Christianity remains, of course, but it is a horrible mythology from a ruler’s point of view, is more or less incompatible with the globalist myths, and has been driven from respectable circles in most of the west anyway. So, the mythologies chosen by the rulers will have to be based upon environmentalism, anti-capitalism, and associated guilt-centric ideas. For lack of a better term, the new mythology will probably have to be globalist, with the many nation states and their scattered strategies being blamed for the crisis. The solution to the crisis, of course, will almost certainly be unified management by proper elites. But if globalist, elite rule is to be the next model, a modification of the social contract will be necessary. This will be the great moment of opportunity for intellectuals. Devising a legitimacy myth for the new order will be a ticket to fame and fortune. As strange as it sounds, there is another group associated with the rulers that must be included in this discussion, and they are the dependent class. People who survive on government checks are not what we usually think of as rulers, but they are necessarily joined to them. Together with the elites, they form a high-low ruling coalition. The vast majority of the dependent will support the rulers (or at least the replacement rulers), almost regardless of what the rulers do. Even if their checks stop, promises of future checks will keep them faithful. The other choice is to utterly reform their lives, and very few will be of any mind to do so. They may complain or even riot at the moment when their checks stop, but being faced with either radical change or supporting the rulers and hoping for restoration, they will choose the latter. And, most unfortunately, this is a very large group. The Other Side Now – and this will not be hard for most of my readers – imagine that you have behaved well and worked hard; that, after being challenged by numerous obstacles, you have carved out a comfortable, stable life. Then imagine that it has been turned upside down. Everything is a mess, and you want things to get back to normal so you can work and enjoy life. What do you do? This is where the formation of the future gets interesting. The Rulers may come up with a few surprises, but their strategies are more or less predictable. The productive ruled, however, are a wild card. Ultimately, they control everything, but they don’t know it. Rulers do not make, they only take. The productive make. If they ever decided, en masse, to stop giving in to the rulers, the rulers would be soundly defeated, and in short order. No matter how many armed tax collectors they employed, it wouldn’t be enough for an unwilling populace, not to mention that paying the armed collectors gets very difficult when there is no more money coming in. And if the mechanic refuses to fix state vehicles, if the HVAC man refuses to fix their air conditioning, and so on, the end comes much faster. The above is precisely what happened at the end of the Roman Empire: Harsher and harsher tax laws brought in less and less silver. People ran away to Germania, Britannia and Gaul to escape. The ruling structure failed. But, as mentioned above, the productive middle does not believe that they have the right to make their own political decisions; they feel free to choose between Party A and Party B, but not to demand a new structure. If, somehow, the productive class does decide they are worthy of such choices, it will be a small matter for them to begin organizing with their neighbors, cobbling together ground-up systems of law and markets, and arriving, over time, at a structure that suits them. They would almost certainly end up rediscovering John Locke, the common law, and sound money. But will they? The Cognitive War Though most of us have seldom realized it, we have been living through a continual war for our minds and our wills. We feel confused a great deal and suspect that it is our own problem; a problem that we hide, rather than risking shame. This equates, roughly, to a surrender in the cognitive war. Anyone who seeks to make us do things without thinking, wages war against our wills. Whole industries are built on this, as we all know: “Look at the pretty, happy people; buy the beer,” “don’t vote for that horrible, scary candidate,” “look here at the sexy girl,” and so on. We all swim in a soup of it. This battle will determine what comes out of Westphalia’s crisis. If the Lockean productive class is too confused and intimidated to assert their wills, the globalists will be able to regroup as they wish. If, somehow, the producers regain their nerve, they can more or less do as they wish. They will have an initial difficulty in overcoming the globalists’ death throes, but in endurance they will reclaim their world. A Second American Revolution The last time a broad group of producers asserted their will and stuck to it was the American Revolution. Contrary to any conventional wisdom of the time, they defeated the mightiest empire on the planet and changed the world. The American Revolution, as I have explained elsewhere, is misunderstood and used badly for propaganda purposes, but it was a unique and potent event. Producers have, at other times, pushed rulers to reform, but very seldom have they gathered the courage to say, “get lost, we’re doing it our way.” In order to achieve this goal the early Americans required separation, Christianity and the philosophy of John Locke. There are wonderful Lockean thinkers and teachers in the West today, but they are usually drowned out by the 24/7 clamor of 500 entertainment channels, music in nearly all public places and the recent Blackberry, texting and iPod fetishes. Withdrawal from the Circus The one real hope for the Lockeans is withdrawal from the great Western circus of mainstream TV, movies and music. In a previous article, I wrote that free news may begin vanishing, and that if it does, people will begin to choose more carefully. The thing I didn’t mention, however, was that this is occurring already. And the people who have been wandering away from the circus are mainly the producers. The first among the Lockeans are headed slowly away from the big noise. These people will begin to reclaim the right to their own opinions, even regarding how they choose to be ruled (or not). If this grows, there will be many people who don’t believe that they need to be coordinated and ordered by central elites and that Adam Smith was right: If you leave people alone, most of them will provide things needed by others, as if guided by an invisible, benevolent hand. In order to avoid this, the globalists will have to preserve media above all. Whether this includes subsidies for cable TV, free Internet services, or whatever, it will be strongly in their interests to provide them. If the circus ends, the young will start to ask impertinent questions. Lockean organization is effective, but it isn’t loud and flashy. Globalist organization is parasitic, but it comes with engaging stories and entertainments. If the circus reigns, the producers stand to be overwhelmed… yet again. The Exercise of Will I leave you with two quotes to consider, and I hope that you do so: The will of men is not shattered, but softened, bent, and guided. Men are seldom forced by it to act, but they are constantly restrained from acting. Such a power does not destroy, but it prevents existence. It does not tyrannize, but it compresses, enervates, extinguishes, and stupefies a people, until each nation is reduced to be nothing better than a flock of timid and industrious animals, of which the government is the shepherd. — Alexis de Tocqueville Mankind is made great or little by its own will. — Friedrich Schiller Paul Rosenberg FreemansPerspective.comlast_img read more

In This Issue Day 2 for Yellen no changes

first_imgIn This Issue. * Day 2 for Yellen, no changes. * N.Z. posts Trade Surplus! * Chinese announce new plans to help economy. * German Unemployment drops by 20,000! And Now. Today’s A Pfennig For Your Thoughts. Gold Shines Brightly On This Tub Thumpin’ Thursday! Good day.. And a Tub Thumpin’ Thursday to you! Well, as I crawled into bed last night, I said to myself, “boy, I sure could use a good night’s sleep tonight”, and I got one! YAHOO! So, maybe that’s the trick, put the idea in my head, and see what happens.. That’s the ticket! Steely Dan greets me this morning with their great song: Aja.. What a great album of the same name that was/ is still today. My good friend, Duane, is a huge Steely Dan fan, and when the music is playing on the Butler patio, he’s always requesting a song or two by Steely Dan. Well, the dollar selling that began with the final words of Janet Yellen’s testimony on Tuesday, continued throughout yesterday, and in the overnight markets. Some of the currencies, like the Aussie dollar (A$), N.Z. dollar / kiwi, Russian ruble, S. African rand, Brazilian real, that have positive rate differentials VS the dollar, are rallying on the thought that their differential will remain in place for now. Other currencies like the euro, are rallying because of good economic data that printed on their behalf. So, let’s look at that first and then move along.. The euro has received a hand basket full of good news this week, and has reacted positively, but the positive reaction has been muted, as if it has a governor placed on it. You know, I use that term a lot, and it just occurred to me that the youngsters that read this letter, have no idea what that means, unless they’ve Googled it, which is the answer to everything these days. No longer does anyone have to wonder what the answer is, all they have to do is Google it! OK, so back to the euro. This morning, the good news came in the form of a better than expected German Unemployment report. The total of unemployed Germans dropped by twice the expected amount in February for a total of 20,000, which kept the Unemployment rate in Germany at 6.5%.. Germany’s economy has weathered the storm, and the lower Oil prices are helping the economy quite a bit, even though it adds to the deflationary environment, that the European Central Bank (ECB) is so frightened of. I so wish that one could simply just buy Germany. But you can’t. when you buy euros, you get all the black sheep of the family coming for Sunday dinner. Ain’t that a shame. My tears fell like rain. Ahhh, Fats Domino on a Tub Thumpin’ Thursday! You can’t beat that with a stick! It was Day Two of Janet Yellen’s trek to Capitol Hill yesterday, and that brought about no changes to her talk on Tuesday, that got the markets all riled up. It was a repeat performance of Tuesday for Yellen. You know yesterday, I attempted to take all the words Yellen used to describe the Fed’s stance on rate changes, and make them understandable. I’m sure it was her wish that the markets all just settle down about a rate hike in June that many not come, and if that’s the case, well, she accomplished what she set out to do. That is, once everyone figured out what it was she was saying. Hey! I never said that the Markets participants are rocket scientists! HA! No the rocket scientists are in the back room of investment houses, brewing up the next, “no lose”, investment idea/ derivative. The one thing for sure that I know and see that Yellen’s testimonies accomplished was getting the 10-year Treasury yield back below 2%… (1.95%) Now, we can’t have the 10-year Treasury, that’s used as the pricing mechanism for mortgage rates, rising, now can we? That would leave a mark on the housing sector, and we certainly can’t have that!  Yes, I’m being a real smart alec right now, and I think I had better stop, before I type out a rant that has to get cut and left on the reviewer’s floor. So, yesterday, I told you how the N.Z. dollar / kiwi was the best performing currency overnight, and last night and this morning, it has continued to add to those gains. Last night N.Z. received the print of their latest Trade Balance, and believe it or don’t, but N.Z. posted a Trade Surplus in January! This is the lowest Trade Balance since June 2013. The thing you have to be suspicious of here is that imports were weak, and that doesn’t bode well for the domestic economy, but on the other side exports were better than expected, so they offset the weak imports sector. All-in-all, a good outcome for kiwi, and the currency has responded accordingly, trading back to 76-cents this morning.. Across the Tasman, Australia printed their 4th QTR CAPEX (capital expenditures, which I always tell you to watch as this is a key to any economy) and the print was not good. 4th QTR CAPEX fell -2.2% which was worse than expectations at -1.6%… the 3rd QTR CAPEX was revised upward from .2% to .6%, so maybe there will be a positive revision to this data down the road. The A$ just let this data slide off its back, or shrugged it off, as traders like to say, and went ahead to rally beside kiwi this morning. We’ll get CAPEX data here in the U.S. today for January. Leading up to January, the previous months’ CAPEX prints left a lot to be desired, and while the January CAPEX print might be positive for once, it won’t be very strong, and that will once again signal to me, and should to the markets and the Fed members that this economy is weak kneed.. The Bond traders know it, and I have to believe that the Fed members know it. At least I sure hope they do, because a rate hike right now would be a tough pill to swallow for the economy. Well, the Russian ruble is posting another strong rally this morning, although it was stronger when I first turned on the currency screen this morning. the beleaguered currency has a very long way to go, which is going to be a tough row to hoe, before it recovers all its losses. Last June, the ruble was trading with a 33 handle, and now it’s finally back to a 60 handle, after seeing the dark side of an 80 handle in December. How long will it be before the economic sanctions that the Eurozone has placed on Russia are relaxed, now that a peace agreement has been in place for nearly 2 weeks? This is key for not only the Russian economy but also the Eurozone economy. So, come on folks, what are you waiting for? So, I guess the Chinese didn’t just sit around eating chocolate bonbons and watching Oprah, while they were out last week, for they came back to work, loaded for bear! The Chinese State Council announced yesterday that they were going to step up fiscal policy support and strengthen targeted controls to combat downward pressure on the economy. A package of tax breaks for small businesses, a reduction of the unemployment insurance tax, which will save businesses over 40 Billion renminbi / yuan annually, and a pledge to speed up construction of major water projects in the less developed central and western regions, are the highlights, and there are more projects in the package that was presented by the State Council. The renminbi / yuan was allowed to appreciate by a small amount overnight as this package of stimulus and tax measures was announced. I like that the Chinese came back ready to tackle the slowdown in the economy. But I have to think that the economy would be just fine without the boost.. But you have to remember that 1. The Chinese have a treasure chest of reserves in which to spend on the economy, and 2. They have to keep the economic ship out to sea, in order to maintain peace in the country. While we’re hanging around Asia.. Singapore received some bad economic data last night in the form of Industrial production (IP)  that fell from the previous month and annually by a large amount, thus surprising the markets by the weakness in IP. Apparently momentum has faltered here, and the Monetary Authority of Singapore (MAS) were correct last month, when they decided to not widen the Sing dollar’s (S$) trading band.  Suddenly, inflation is not a problem in Singapore, and therefore the MAS doesn’t need a stronger S$ to combat inflation that isn’t there. the deflation bug has landed on Singapore’s shores, and spread quickly. the bug originated in Japan, folks. Speaking of Japan. this basket case of a country, has been pretty quiet lately. And the Japanese yen has benefitted from this quietness. Now, don’t get me wrong here, I’m not saying that yen is about to go on a rally to the moon. I’m just talking about this brief little rally while things are quiet in Japan. That’ll all change soon enough, it always does with the Japan… Well, coming back closer to home, Canada will print their January CPI (consumer inflation) today, and it’s expected to print around 2.1%, thus a notch above the Bank of Canada’s (BOC) inflation target of 2%.. BOC Gov. Poloz has been dangling a rate cut in front of the markets like a carrot on and stick, but a CPI print of 2.1% will not help him one iota. And he’ll have to put the stick and carrot away for another month. So watch this data print closely, because if Canadian CPI would happen to fall below 2%, Poloz will be dancing in the street, because he’ll get to cut rates again, and knock the stuffing out of the Canadian dollar / loonie. Speaking of CPI. We might as well head to the U.S. Data Cupboard and see what it has for us today. Open it up and WOW! It is stocked! First up is the stupid U.S. CPI, which will most likely print a large negative number that will all but nail down the Fed to not hiking rates in June at this point. Next up is real data, as U.S. Durable Goods Orders print for January and is expected to finally print a positive number, after 3 previous prints that were devastatingly disappointing. Then the usual Tub Thumpin Thursday print of Weekly Initial Jobless Claims, the 4th QTR Home Price Index, and Bloomberg Consumer Comfort index.   Yesterday’s Data Cupboard had January New Home Sales, which edged downward by -.2%… I suspect this data to be back and forth in 2015, as rate hike talk slows things down, only to be reversed when the rate hike doesn’t happen. Back and forth, a real wishy-washy year for New Home Sales, in my opinion, which could be wrong, of course! I went nearly the whole letter and didn’t mention the $12 gain in Gold this morning! Silly me. I was thinking that I shouldn’t get all lathered up over a nice gain like that early in the morning, before the NY traders arrived at their desks, and “took care of that little problem”. But then I got here and it was still there, and I thought. Oh well, at least it was a nice gain when I was writing the Pfennig!  But with Yellen reinforcing her talk from Tuesday, Gold was able to take advantage and move past $1,200 yesterday, and then add another $12 this morning.  My spider sense is tingling right now. I wonder what’s up here? Yesterday I highlighted the fact that Palladium had made one of its legendary “jumps” , and today it’s Platinum’s turn, as it hangs a $20 gain on yesterday’s figure. For What It’s Worth. Well, my friends Dave Gonigam and Addison Wiggin over at Agora’s 5 Minute Forecast were kind enough to quote me in their letter yesterday and use some of the stuff I said about Yellen’s testimony. I love it when I see my name up in lights!   On a sidebar, I picked up a book in the library here in the building the other day, and began reading it, and one of the principal characters in the story is guy named: Charles Butler..  Now How about that! Well, I thought I would return the favor to by friends over at the 5 Minute Forecast and reprint something they had in their letter yesterday. This is a note that Addison Wiggin printed 5 years ago from someone in China. Now remember this is 5 years ago in China. “What people fail to grasp,” this individual wrote, “is this place is much more capitalist than the States now: .               No capital gains tax .               No property tax .               No local or state taxes .               A reasonable 35% tax rate for the highest earners .               Corporate tax rates of 0% for three years and 15% per year after that.             “Also, most importantly, it’s not a casino economy like the States. China will sell 30% more vehicles this year than in the U.S, and 93% of those vehicles will be purchased cash up front. “For a home loan, you need 30% down. As a private business, to get a loan, you have to put up the assets of the company, i.e., plant and equipment. There are no leverage games here. “It’s a one-party state, but at least it is focused on its own people. We have a two-party system that has sold us down the river. All the Asian Tiger economies needed a strong central government to launch themselves out of poverty. Not a good system for our culture, but it works for them. “High-speed train systems going on line, 50 new airports in that last five years — you must see this place to believe it.” Chuck again. Yes, and there are still naysayers about China’s economy and the direction of the country.. That’s amazing to me for sure! To recap. Yellen speaks again, no changes to her first testimony, so the dollar selling continues. the positive rate differential currencies put in the best performances overnight, and the euro rallies on good labor data from Germany. New Zealand posts a Trade surplus, which is strange for them, and Australia prints weak CAPEX data but shrugs it off and the A$ rallies. Gold is up $12 this morning, and China announces new plans to stimulate economy, Chuck sure hopes they don’t start down the path well beaten down by the Japanese. Currencies today 2/25/15. American Style: A$ .7905, kiwi .7600, C$ .8030, euro 1.1360, sterling 1.5510, Swiss $1.0540,  . European Style: rand 11.4055, krone 7.5500, SEK 8.3020, forint 267.05, zloty 3.6640, koruna 24.2020, RUB 60.47, yen 118.80, sing 1.3505, HKD 7.7545, INR 61.75, China 6.1379, pesos 14.85, BRL 2.8450, Dollar Index 94.28, Oil $50.58, 10-year 1.95%, Silver $16.82, Platinum $1,190.88, Palladium $811.25, and Gold. $1,218.10 That’s it for today. Well. the first full squad workout of Spring Training for my beloved Cardinals took place yesterday. Next Saturday, is the first home Spring Training game of 2015 for the Cardinals. Spring Training games are impossible to fill in a score card, because there are so many changes with players, pitchers, positions, etc. so, you just go and enjoy the beautiful day, the sounds, the smells and baseball.. Can you believe that February is almost over? The month flew by like the wind. I sure hope March lasts a lot longer! The other night my beloved Missouri Tigers finally stopped their 13 game losing streak and beat the mighty Florida Gators! And the St. Louis U. Billikens are looking to win 2 in a row! Maybe things will look brighter for these two schools’ beleaguered basketball teams heading into March.. Jimi Hendrix is playing: All Along the Watchtower on the iPod right now. And that tells me that the watchtower has struck the bewitching hour of when this needs to get out of here! So, make sure you go out and have a Tub Thumpin’ Thursday! Chuck Butler Managing Director EverBank Global Marketslast_img read more

By Nick Giambruno Editors note Today we have a

first_imgBy Nick Giambruno Editor’s note: Today we have an urgent essay to share with you from Crisis Investing editor Nick Giambruno. You see, right now, a dangerous shift is playing out in Europe… one that could change the continent’s political landscape in a way not seen since before World War II. As Nick explains below, it all has to do with tomorrow’s important vote. Read on to get the details on how it will all go down—and what it could mean for you and your fellow Americans… Tomorrow, a vote in the Netherlands could push the euro and the EU one step closer to death… For the last several months, I’ve been warning readers about a populist tsunami washing through Europe. It’s drastically changing the continent’s political landscape in a way not seen since before World War II. This wave is flushing away traditional “mainstream” parties. And it’s bringing in anti-establishment populists who want to leave the euro currency and the European Union. It’s already hit the UK in the form of Brexit, killing David Cameron’s pro-EU government in the process. Then it struck Italy, washing away pro-EU Matteo Renzi’s government. After spending a few weeks in Italy last year, months in advance, I predicted the country’s constitutional referendum would fail and Renzi would resign. (I’m also an Italian citizen.) That’s why I advised Crisis Investing subscribers to short the euro with an investment that trades like any ordinary U.S. stock. As of writing, we’re sitting on a double-digit gain, but I expect there’s a lot more upside in the months ahead. Tomorrow, on March 15, the populist wave is set to hit the Netherlands. That’s when Dutch voters go to the polls. The anti-EU populist Party for Freedom is expected to win. It’s led by Geert Wilders, who was close to Trump’s campaign. Some even call him the “Dutch Trump.” Leaving the euro is a top priority for the Party for Freedom. If it wins, it would be another nail in the coffin for the European currency. Either way, the Dutch parliament will discuss how to leave the eurozone shortly after the March 15 election. A top lawmaker recently said that “the probe will examine whether it would be possible for the Dutch to withdraw from the single currency, and if so how,” Reuters reported. The euro’s problems are compounding and could get much worse, very soon. Germany (September 24) France (April 23) Why 2017 Could Offer a Rare “Second Chance” to Get Rich in the Stock Market Imagine waking up to find the size of your retirement account has doubled… all thanks to a small $500 investment. It sounds impossible… But this sort of thing has happened before. Could it happen again? Click here for the full story. These elections will ultimately determine the fate of the European Union. The Brexit vote, Donald Trump’s election, and the failure of Italy’s constitutional referendum have already boosted anti-euro populist parties in these countries. If the Party for Freedom wins in the Netherlands tomorrow, they’ll get another leg up. Populist parties have a real chance to win in both France and Germany. But even if they win in just one, the EU would likely unravel. The biggest issue in these elections is the migrant crisis, which we’ve covered here extensively. And the crisis is only accelerating. Every single migrant that arrives in Europe increases the chance that anti-EU populists will win a key election. That’s not good news for the EU or the euro. It’s also not good news for the U.S. Whatever happens in the EU—the world’s largest economy and a major U.S. trading partner—matters. If the euro collapses, expect it to trigger a stock market collapse in the U.S. The Financial Times recently put it this way: It would probably lead to the most violent economic shock in history, dwarfing the Lehman Brothers bankruptcy in 2008 and the 1929 Wall Street crash. And it could all begin unfolding tomorrow… Regards, — Two of Europe’s biggest countries have elections this year: Nick Giambruno Editor, Crisis Investing P.S. Tomorrow, March 15, is a crucially important date for Americans, too. Especially those who have any money in the stock market. Because on that day, the debt ceiling deadline hits. If Congress can’t come together to agree on a solution, the Treasury could run out of money. In the worst case, this could affect Social Security and government pension funding. Also, the last time the debt ceiling battle got fierce, the U.S. credit rating was downgraded. If that happens again, there could be big trouble in the markets. On top of the debt ceiling deadline, the Federal Open Market Committee (FOMC) will meet tomorrow—and all signs are pointing to a rise in interest rates. A steep series of rate increases could also spell doom for the market. That’s why Casey Research founder Doug Casey and I put together this urgent video designed to help you navigate markets in crisis… You can watch it here. How Doug turned every $1,000 into $86,000 An unusual group of companies I call “penny fuel stocks” are on the verge of a historic boom. Only TWICE in history has a similar event happened… and each time, these tiny stocks roared for 10-, 100-, some even saw rare but life-altering 1,000-fold returns. We know this because our research firm’s founder, Doug Casey, saw these returns himself. In fact, he saw a life-altering 86-fold return! These types of life-altering gains are something most investors never have the opportunity to see but now, thanks to the Trump administration, this same energy event is happening right now. And Doug and his team are now recommending plays with similar life-changing potential! Click here for full details. – Recommended Linkslast_img read more

UCLA biologists uncover how head injuries can lead to serious brain disorders

first_img“Knowing which genes in which cells are changing in a particular person can lead to the right treatment for that person,” said Yang, who is a member of UCLA’s Institute for Quantitative and Computational Biology.Gomez-Pinilla, who also is a member of UCLA’s Brain Injury Research Center, describes the new research as an advance in precision medicine, which holds the promise of individualized treatments for diseases. Reviewed by Alina Shrourou, B.Sc. (Editor)Nov 17 2018UCLA biologists have discovered how head injuries adversely affect individual cells and genes that can lead to serious brain disorders. The life scientists provide the first cell “atlas” of the hippocampus — the part of the brain that helps regulate learning and memory — when it is affected by traumatic brain injury. The team also proposes gene candidates for treating brain diseases associated with traumatic brain injury, such as Alzheimer’s disease and post-traumatic stress disorder.The researchers studied more than 6,000 cells in 15 hippocampal cell types — the first study of individual cell types subject to brain trauma. Each cell has the same DNA, but which genes are activated varies among different cell types. Among the 15 cell types are two that were previously unknown, each with a unique set of active genes.”Every cell type is different,” said Fernando Gomez-Pinilla, a UCLA professor of neurosurgery and of integrative biology and physiology, and co-senior author of the study, which was published in the journal Nature Communications.The biologists found that hundreds of genes are adversely affected by mild traumatic brain injury, such as a concussion. These altered genes can later lead to Alzheimer’s, Parkinson’s and other diseases.The researchers reproduced a concussion-like brain injury in mice, and studied other mice that did not receive a brain injury. The researchers analyzed thousands of cells in the hippocampus of both groups of mice. Among their findings: The mice without an injury had very low levels in 14 of the 15 cell types of a gene called Ttr that regulates metabolism, controls thyroid hormones and performs other functions. Brain trauma increased the level of Ttr in essentially all of the cell types, the researchers found. They concluded Ttr is important to brain health and may function to bring more thyroid hormone to the brain to maintain metabolism. A thyroid hormone called T4 was injected in mice. T4 improved traumatic brain injury-induced learning deficits and reversed changes in 93 genes that affect learning and memory. This reversal in damage caused by traumatic brain injury is a major new finding. After brain injury, metabolism is substantially reduced. The biologists think T4 may “reboot” metabolism. Researchers found evidence that at least 12 of 15 cell types are negatively affected by brain trauma, some more strongly than others. The researchers were able to see how genes that have been linked to Alzheimer’s disease acted within different cell types, providing new details about where these genes act when they are affected by brain trauma. “We are learning which cell types we may want to target in future research,” said Xia Yang, a senior author of the study and a UCLA associate professor of integrative biology and physiology. “Maybe Alzheimer’s disease-related genes do not have to be active in all different cell types.” For the first time, the biologists found several genes that are affected by traumatic brain injury, which has recently been linked to neurotic behavior in humans. Traumatic brain injury has been associated with depression, anxiety and schizophrenia. This research could lead to new treatments for these conditions. Injury to the brain can lead to what is known as post-traumatic epilepsy. The researchers found a gene that could serve as a potential target for treating this kind of epilepsy. Traumatic brain injury causes changes in how cells communicate with one another (see attached image).center_img Source:http://newsroom.ucla.edu/releases/ucla-cell-study-reveals-how-head-injuries-lead-to-serious-brain-diseaseslast_img read more

A new treatment for Chlamydia via Canadian researchers

first_imgThe study was titled, “Autophagy induction and PDGFR-β knockdown by siRNA-encapsulated nanoparticles reduce chlamydia trachomatis infection.” Further Reading Chlamydia 3D illustration. Credit: Tatiana Shepeleva / Shutterstock What is Chlamydia? Chlamydia Infection Pathophysiology Chlamydia Screening Chlamydia Diagnosis Chlamydia Treatmentcenter_img By Dr. Ananya Mandal, MDFeb 6 2019A new way to prevent and treat one of the commonest sexually transmitted infections (STIs) has been developed by the researchers at the University of Manitoba and the University of Waterloo. This new method is more of a gene therapy than antibiotic therapy against the infection. The results of the study outlining the therapy were published in the latest issue of the journal Scientific Reports. For this new study researchers Sidi Yang, Yannick Traore, Celine Jimenez and Emmanuel A. Ho experimented with a gene therapy that is delivered with the help of nanotechnology. Results showed a 65 percent success rate in prevention of the infection after a single dose of the gene therapy. Emmanuel Ho, a professor at Waterloo’s School of Pharmacy and lead researcher said, “As antibiotic resistance continues to develop, people may experience Chlamydia infections that cannot be treated through conventional means, which is causing increasing public health challenges. If left untreated or if treatment takes an extended period of time it can lead to infertility and other reproductive issues so finding new ways to treat this common infection is important.” He explained that the FDA has recently approved the first “siRNA-based drug” and this could soon be available for use.For this approach the team targets Chlamydia infection by preventing the bacteria from entering the cells in the genital mucosa. The approach also kills bacteria that have managed to penetrate the cells. The team used a small interfering ribonucleic acid (siRNA) to target a gene called PDGFR-beta in the mucosa of the female genital tract. This gene is responsible for making a protein that eventually binds to the Chlamydia bacteria. Ho explained that if they targeted this gene they could stop the production of the protein that Chamydia can use when it enters the female genital tract. “As a result, an incoming infection has fewer targets to latch onto and infection is less likely to occur,” he said. The treatment takes a step further. The Chlamydia that already has entered the dells are killed by the process of autophagy. The infected skin cells form a coating or bubble around the bacteria and kill it.The authors conclude in their study that this new method has been proven to be effective in the lab situations. Further studies can prove its efficacy in real life scenarios. Recent data from the Centers for Disease Control Prevention (CDC) shows that there is an increase in incidence of STIs such as Chlamydia, Syphilis and Gonorrhea and with rise of antibiotic resistance, treatment is becoming difficult. If this gene therapy is successful, new avenues in STI management could open up.Source: https://www.nature.com/articles/s41598-018-36601-ylast_img read more

Google search serves up Wimbledon tennis minigame

first_imgGoogle’s tennis game is hidden inside a dedicated Wimbledon 2019 search results box. — AFP Relaxnews Related News The game is a straightforward yet pleasing enough adaptation of lawn tennis (and its classic 1960s and 1970s video game adaptations).A player-controlled character sets up on one side of a tennis court, their opponent on the other.Players tap on the left or right side of the screen (or use arrow cursor keys on desktop) to serve the ball and then move their athlete from one side to the other.Athletes hit the ball automatically should they connect, with players exerting no influence over direction.However, the ball’s speed increases with each touch until the player makes a critical error.Characters appear to be predominantly anthropomorphic, with goats, corgi dogs, bears, bunnies and foxes popping up during our time with the game; astronauts, luchadors, and Google Android’s mobile OS mascot also popped up.Data from the reaction-based game could allow Google to extrapolate other information about players’ age, cognitive ability, and so on, especially in combination with previously collected details.Over a dozen championship titles are to be decided at the 2019 Wimbledon tennis tournament.The Ladies’ Singles Final, Men’s Doubles Final, and Ladies’ Doubles Final take place on July 13.The Men’s Singles Final and Mixed Doubles Final take place on July 14.In addition, Finals for the Boys’ and Girls’ Singles and Doubles competitions, the Men’s and Ladies’ Singles and Doubles disciplines, the Men’s and Ladies’ Wheelchair Singles and Doubles Finals, Quad Wheelchair Singles Final, and the Invitation Doubles all take place over the weekend.Various matches begin at 11am, 1pm, and 2pm BST (6pm, 8pm and 9pm Malaysia), with Order of Play details decided the night before. – AFP Relaxnews Tennis 09 Jul 2019 Serena wants Murena mixed doubles team name Related News Tennis 09 Jul 2019 Tennis-Wimbledon day eight Internet giant Google has inserted a hidden tennis game into related search results to mark the 2019 Wimbledon tennis championships, whose finals take place over the weekend of July 13 and 14.Lest it go undiscovered before Britain’s Wimbledon Championships conclude this weekend, Google wants to make sure people know about its tribute to the year’s penultimate Grand Slam tennis tournament.Searching for Wimbledon-related results brings up a dedicated results box containing match information.Scrolling past headers for singles and doubles matches reveals a green tennis ball – clicking or tapping on it prompts a pixel-art tennis game to load. Tennis 08 Jul 2019 Murray confident of return to top of men’s tennis {{category}} {{time}} {{title}}last_img read more